The results showed that the expressions of SEC61A1, A2, and B in HNSCC were higher than those in normal control tissues by UALCAN online tool, respectively (Figure 7A, p < 0.001; Figure 7C, p < 0.001; and Figure 7E, p < 0.001). The gene discussed is SEC61A1; the disease is head and neck squamous cell carcinoma.