However, in our study, LRG1 expression in colon cancer tissue was lower than that in normal colon tissue (relative abundance LNMC/NC = 0.668, RNMC/NC = 0.839), although the levels in RNMC were still higher relative to LNMC (RNMC/LNMC = 1.257). Here, LRG1 is linked to malignant colon neoplasm.