Conversely, NMZLs display an inactivation of PTPRD (14% in NMZLs vs. 3% in MALT lymphomas) and a much higher prevalence of mutations affecting KMT2D (34% in NMZL vs. 15% in MALT lymphomas) [13,16]. Here, PTPRD is linked to nodal marginal zone B-cell lymphoma.