ENSG00000280371 and esophageal cancer: Another potential candidate is CAV1 (caveolin-1), located at 7q31, which can act either as an oncogene (as described in bladder, thyroid, and esophageal cancers) or as a tumor suppressor gene (in ovarian, lung, and mammary tumors), depending on the tissue type or the microenvironmental influence [22].