In primary pancreatic tumors, ARL4C ASO-1316 reduced ARL4C expression at protein and mRNA levels (Figure 7H; Figure 7—figure supplement 1B) and decreased the localization of IQGAP1 to the cell surface area (Figure 7I; Figure 7—figure supplement 1C). This evidence concerns the gene IQGAP1 and pancreatic neoplasm.