The expression level of VEGF, pVEGFR2, PI3K, p‐PI3K, AKT, p‐AKT, ERK1/2, p‐ERK1/2 and Ki‐67 in tumour tissues harvested from the xenograft model was determined by immunohistochemical analysis (Figure 5). The gene discussed is MAPK3; the disease is neoplasm.