MYO1D and colitis: MYO1D gene knockout in different mouse strains (seven different strains) is shown to demonstrate a variety of phenotypes like decreased body fat amount (adipose tissue), decreased startle reflex (behaviour/neurological), increased susceptibility to colitis (digestive/alimentary), decreased bone mineral content (skeleton), and increased susceptibility to weight loss (growth size/body weight and immune system and mortality or ageing) (Figure 5).