Among pyroptosis-related genes, GPX4, NLRP7, CASP6, CASP3, IL1B, IL18, CASP8, NLRP6, IL6, GSDMC, PYCARD, AIM2, NOD2, NLRP3, and CASP4 were aberrantly expressed in breast cancer. Here, NLRP6 is linked to breast carcinoma.