Assistant with the expression in TCGA, the expression of ALYREF, DNMT1, DNMT3A, DNMT3B, NOP2, NSUN3, NSUN4, NSUN5, NSUN6, NSUN7, and TET2 were higher in HCC cell line Huh7 than in normal cell line L02. The gene discussed is NSUN4; the disease is hepatocellular carcinoma.