NFKB1 and cancer: NF-κB not only is a critical transcription factor for HIV RNA synthesis, but also a factor that facilitates cell proliferation in many cancers (Kretzschmar et al., 1992; West et al., 2001; Biswas et al., 2004; Hayden et al., 2006; Xia et al., 2014; Blakely et al., 2015).