For m6A writers, METTL3 was reported to be upregulated in 13 types of cancers and serve as an oncogene in which METTL3 can regulate the differentiation and apoptosis, survival, and metastasis of cancers containing glioma via influencing the translation, stability, and AKT pathway of oncogenes, tumor suppressors, and miRNAs. The gene discussed is METTL3; the disease is glioma.