To explore whether key glioma-related m6A RNA methylation regulators (KIAA1429, METTL16, METTL3, IGF2BP2, and YTHDF1) and targets (COL18A1, NASP, PHLPP2, TIMP1, U2AF2, and VEGFA) were associated with anticancer drug responses, we performed a correlation analysis between the expressions of these genes and drug susceptibility using CellMiner database and R packages impute, limma, ggplot2, and ggpubr. This evidence concerns the gene PHLPP2 and central nervous system cancer.