In this in vitro study, we had demonstrated that the human omentum adipocytes consistently express antimicrobial peptides (LL-37, HNP 1-3, HBD-1 and HBD-2) and cytokines (IL-1b, IL-2, IL-4, IL-8, IL-10, TNF-α, and GM-CSF) in a dose-dependent manner to increasing concentrations of LPS, mimicking experimental sepsis and the extent of its severity. Here, IL1B is linked to Sepsis.