Researchers focused on four variables of VDR gene polymorphism - namely ApaI (VDR 7975232 C > T), BsmI (VDR 1544410 A > G), FokI (VDR 2228570 C > T), and TaqI (VDR 731236 T > C) - and reported that MetS is significantly associated with ApaI gene polymorphism. The gene discussed is VDR; the disease is metabolic syndrome.