Table 5 shows gene signatures selected by each method. ALASSO, AENET, SCAD, SCAD-L2, MCP, MCP-L2, and Boosting selected 18, 19, 26, 22, 20, 21, and 12 genes, respectively. As can be seen, there are several genes that are related to bladder cancer biologically. Among all genes selected, there were six genes of CDC20, NCF2, SMARCAD1, RTN4, ETFDH, and SON selected by all methods.  Table 6 shows regression coefficients of six common genes selected by all methods correlated with bladder cancer patients' subdistribution hazards. The gene discussed is RTN4; the disease is urinary bladder carcinoma.