These findings showed that risk score was negatively correlated with abundance of resting immune cell (i.e., resting memory CD4 + T cells, etc.), whereas it was positively correlated with immunosuppressive cells (i.e., cancer-associated fibroblast, Tregs, etc.), indicating low-risk score patients were immune resting phenotype, whereas high-risk score represents immunosuppressive tumor microenvironment. Here, CD4 is linked to cancer.