Zanella et al. (2019) found a modern-specific enrichment for regulatory changes both in the human BAZ1B and its downstream targets. Finally, in people with WS, the OXTR gene is found hypomethylated, seemingly as a result of the altered functioning of methyltransferase genes located within the WS locus (Haas and Smith, 2015). This evidence concerns the gene OXTR and Werner syndrome.