However, no significant differences were found, which is in line with previous studies finding diverging results (Stigsby et al., 1981; Besthorn et al., 1996; Yener et al., 1996; Passant et al., 2005) and the relative alpha was not lower in patients with CHMP2B-FTD. The gene discussed is CHMP2B; the disease is frontotemporal dementia.