MAPT and Mental deterioration: When entFTP was additionally included as predictor, cMD in the isthmus cingulate cortex remained a significant predictor of cognitive decline (Supplementary Table 3); when i-tFTP was used as predictor instead of entFTP, none of the regional cMD values remained predictive of cognitive decline, suggesting that the shared variance between cMD and subsequent cognitive decline is explained by increased neocortical tau pathology.