Among modifications of plasma proteins, probably associated with the tumorigenesis, researchers note the role of alpha-1-antitrypsin (A1AT) nitrosylation in the regulation of apoptosis31, glycosylation and fucosylation of A1AT in ovarian and breast cancers28, fucosylation and sialylation of apolipoprotein C3 (APOC3) in colorectal cancer as well as fucosylation C3 complement in colorectal cancer41, and glycosylation of serotransferrin (TRFE) in oncology42. Here, APOC3 is linked to colorectal cancer.