Dysregulation of the c-Myb pathway provides the basis for adult T-cell leukemia/lymphoma cells [31], and high expression of c-Myb in tumor tissues may be a predictor of poor prognosis for Burkitt lymphoma patients [32], illustrating that c-Myb dysregulation is actively involved in the pathogenesis and prognosis of lymphoid tumors. The gene discussed is MYB; the disease is Burkitt lymphoma.