Many studies revealed the oncogenic roles of CHD1L in different kinds of malignancies, such as ovarian carcinoma [3], bladder cancer [4], colorectal carcinoma [5], breast cancer [6], and lung adenocarcinoma [7], etc. Considering that dysbacteriosis is common in cancer patients, it is important to know how CHD1L works in the pathological microenvironment of dysregulated flora. Here, CHD1L is linked to colorectal carcinoma.