The results showed that JAK1 expression was negatively correlated with tumour purity (r = − 0.229, P = 2.73e-07) and significantly positively correlated with infiltrating levels of B cells (r = 0.155, P = 6.20e−04), CD8+ T cells (r = 0.307, P = 4.41e−12), CD4+ T cells (r = 0.422, P = 2.42e−22), macrophages (r = 0.342, P = 9.91e−15), neutrophils (r = 0.459, P = 1.41e−26), and dendritic cells (r = 0.479, P = 2.25e−29). The gene discussed is JAK1; the disease is neoplasm.