CRP and major depressive disorder: Therefore, considering the clinical demands for validation of a useful set of molecules and biological processes that can cooperate in MDD and may help in medical practice, in this work we proposed to test some specifics peripheral molecular parameters, such as CAR, SC, mBDNF and CRP, as well as the Pittsburgh sleep quality inventory (PSQI), as part of a multibiomarker panel for diagnosing and evaluating the chronicity of MDD.