KMT2A and acute myeloid leukemia: Because MS67’s GI50 values in PDAC cells such as MIA PaCa-2 (8100 ± 2,600 nM) and HPAF-II (3700 ± 280 nM) were much higher than that in MV4;11 cells (15 ± 8 nM), we chose to use the MV4;11 MLL-r AML xenograft mouse model for in vivo efficacy studies.