PRDM16 and cardiomyopathy: SNP rs4483351 was located on PR/SET domain 16 gene (PRDM16, OMIM accession number: 605557), which was found to have connection with cardiomyopathy (Arndt & MacRae, 2014; Arndt et al., 2013), thus it might could play an important role in regulating blood pressure.