CDH1 and cancer: The reduction of E-cadherin might be due to alteration of Fusobacterium nucleatum adhesin FadA, which is required for attaching E-cadherin on epithelial cells to mediate Wnt/β‐catenin signaling.97,98 In a later study, cholic acid-fed Apcmin/+ mice showed an increase in the mucin-degrading bacteria (Akkermansia and Bacteroides) and a decrease in SCFAs and MUC2 expression, resulting in cancer progression via STAT3 signaling.99 Therefore, understanding the association between BAs and microbiota on intestinal epithelial cells is important in mucosal physiology.