Furthermore, increased GCF (gingival crevicular fluid) IL-1β levels have been associated with the aetiopathogenesis and progression of cardiovascular and periodontal diseases.20,32,35 In a recent study, Taşdemir et al42 assessed the GCF suPAR and galectin-1 levels among patients with gingivitis and periodontitis and compared them with periodontally healthy individuals (controls). Here, LGALS1 is linked to periodontitis.