Difference analysis results showed age (P < 0.001), hypertension (P = 0.002), BMI (P < 0.001), ECOG PS (P < 0.001), KPS (P < 0.001), physical activity (P < 0.001), serum total protein (P < 0.001), serum albumin (P < 0.001), AST (P = 0.004), ALT (P = 0.0019), haemoglobin (P < 0.001), WBC (P < 0.001), neutrophils (P < 0.001), lymphocytes (P = 0.002), and PNI (P < 0.001) has different significance in the GNRI grouping population (Table1). The gene discussed is ALB; the disease is Hypertension.