On the other hand, for Score2, gossypol (Score2 = −0.66) and menadione (Score2 = −0.65) were exhibiting highly negative values and were also supported by literature, since administration of gossypol combined with gemcitabine has been shown previously to synergistically inhibit growth of gemcitabine-resistant pancreatic cancer cells with high BCL-2 expression (Wong et al., 2012). The gene discussed is BCL2; the disease is familial pancreatic carcinoma.