For example, the gene MAD1L1 (a component of the mitotic spindle-assembly checkpoint) was shown to be a risk factor for PTSD in GWAS and EWAS studies (Snijders et al., 2020; Stein et al., 2021), and has also been shown to be associated with ANX (Levey et al., 2020), revealing shared pathways across the different stress-related disorders, in line with their genetic overlap. Here, MAD1L1 is linked to post-traumatic stress disorder.