MAD1L1 and post-traumatic stress disorder: A longitudinal EWAS for PTSD which meta-analyzed 3 male military cohorts (123 cases and 143 controls) found 3 epigenome-wide significant CpGs-one of which was intergenic while the other 2 were located in genes MAD1L1 and HEXDC. In addition, 12 significant differential methylated regions (DMRs) were found; 4 of these regions were located in the human leukocyte antigen (HLA) and 1 was situated in MAD1L1 (Snijders et al., 2020).