MXD3 and cancer: We explored the oncogenic role of MXD3 across the TCGA pan-cancer database and found that mRNA levels of MXD3 were significantly (p < 0.05) overexpressed in tumors of all TCGA cancer types compared to their corresponding adjacent normal tissues, except for kidney chromophobe (KICH), pancreatic adenocarcinoma (PAAD), and skin cutaneous melanoma (SKCM) (Fig. 3, Supplementary Fig. 1).