In-depth analysis of PCa patients that had undergone radical prostatectomy, revealed significant higher gene expression profiles for ACAT1 (P = 0.0006) and OXCT1 (P = 0.0009), in PCa patients that biochemically relapsed (BCR) within a five-year follow-up period, as compared with patients that did not relapse in the same time-period (No BCR) (Fig. 6A). The gene discussed is ACAT1; the disease is posterior cortical atrophy.