After introducing smoking, sex and BMI, the main effect of CRP (log10) did not remain significant (F(2,98) = 2.167, p = 0.120), while it did not alter the main results of CCL20 (F(2,90) = 6.559, p = 0.001, post hoc: HC < SZ p = 0.002, MDD < SZ p = 0.002, HC vs MDD p = 0.483) and TRAIL (F(2,90) = 6.377 , p = 0.003, post hoc: HC < SZ, p < 0.001, HC < MDD p = 0.003, SZ vs MDD p = 0.625 (new: non-significant)). This evidence concerns the gene CRP and major depressive disorder.