Further, there were no significant correlations between smoking and CRP (HC: r(s) = 0.152, p = 0.59; SZ: r(s) = 0.302, p = 0.06; MDD: r(s) = − 0.089, p = 0.62) nor CCL20 (HC: r(s) = 0.057, p = 0.84; SZ: r(s) = 0.190, p = 0.24; MDD: r(s) = 0.320, p = 0.054) nor TRAIL (HC: r(s) = 0.371, p = 0.17; SZ: r(s) = 0.258, p = 0.11; MDD: r(s) = 0.267, p = 0.12) (analyses were controlled for BMI and sex). Here, TNFSF10 is linked to major depressive disorder.