OSBPL3 was overexpressed in tumor tissues compared with normal tissues in almost all cancers evaluated (Fig. 5c), and high OSBPL3 expression was significantly associated with poor prognosis in colon cancer, pancreatic cancer, liver cancer, bladder cancer, and lung adenocarcinoma (Fig. 5d–h). The gene discussed is OSBPL3; the disease is malignant colon neoplasm.