However, when we quantified ATP5B, its expression in NK cells from HCMV− participants was maintained at baseline levels at Days 7 and 28 post-ChAdV prime in both CD56dim and CD56bright NK cells (Fig. 3g), but was consistently downregulated in HCMV+ participants at these times, suggesting selective downregulation of components of mitochondrial ATP synthase in individuals that had prior exposure to HCMV infection. This evidence concerns the gene ATP5F1B and cytomegalovirus infection.