Additionally, conditioned medium obtained from RNF144A-AS1-silenced MKN45 (CM-MKN45) and AGS (CM-AGS) cells progressively decreased the tube-formation rate of HUVECs, suggesting attenuated tumor angiogenesis by the knockdown of RNF144A-AS1 (Fig. 2E, F). Here, RNF144A is linked to neoplasm.