In line with decreasing levels in advanced plaque/tumor lesions, the markers CD69, HSPA1A and ZFP36 showed significantly higher expression levels in patches of early-stage MF in comparison to patches from advanced-stage MF (Fig. 6 E), while other T subsets (helper T cells, cytotoxic T cells, regulatory T cells) again did not consistently harbor such differences (Table S8). This evidence concerns the gene HSPA1A and mycosis fungoides.