CXCR4 and neoplasm: We also assessed marker expression of lymphoma cells isolated from three patch and five plaque/tumor MF skin lesions by flow cytometry-based cell sorting (Fig. S3A-B), confirming similar decreases in all markers except for TXNIP. These data suggest that CXCR4, CD69, HSPA1A, ZFP36, IL7R (and possibly TXNIP) represent potential markers of disease progression that are common to the malignant clone in the three MF patients investigated.