Markers predominantly found in tumor cells of early-stage MF lesions included cytotoxic molecules such as GNLY, GZMA, GZMB and GZMH, as well as a broad array of inflammatory cytokines/chemokines such IFNG, CCL4, CCL1, CSF2, CCL3, CCL20, IL26, XCL1, and XCL2 (Fig. 6 F). This evidence concerns the gene GZMB and neoplasm.