Several genes were upregulated in MS + Enr (n = 24) animals compared to controls (n = 24), including CALM1 (t(46)=4.307, p < 0.000), ESR1 (t(46)=2.520, p = 0.015), FOXO1 (t(46)=2.137, p = 0.038), GABRA1 (t(46)=2.384, p = 0.021), IL10RB (t(46)=2.271, p = 0.028), KALRN (t(46)=3.634, p = 0.001), PIK3CB (t(46)=3.077, p = 0.004), TBP (t(46)=2.307, p = 0.026), TRAF6 (t(46)=2.320, p = 0.025), TSC22D3 (t(46)=2.313, p = 0.025), and WNT2B (t(46)=2.697, p = 0.010). This evidence concerns the gene KALRN and myeloid sarcoma.