Our IPA analysis showed that activation of cytokines IL6, IL16, CXCL1, CXCL3, CXCL5, CXCL6, CXCL8, CXCL10, and CCL20 are a hallmark signature of cytokine response in COVID-19 patients [21, 22]. Here, CXCL6 is linked to COVID-19.