Endogenous concentration of CoQ10-TOTAL (ubiquinone + ubiquinol) in platelets of RA_ALL patients significantly decreased to 57.79% (p<0.0001), in group RA_CRP decreased to 59.42% (p<0.01) and in RA_CVD group to 87.02% (not significant) vs control group. This evidence concerns the gene CRP and acute lymphoblastic leukemia.