CDK4 and melanoma: In the GSE32474 dataset, the expression levels of CDK2, CDK4, KIT, and VWF in the melanoma metastasis group were significantly higher than those in the melanoma primary focus group (t = 2.616, 2.244, 2.137, and 2.570, respectively; logFC = 1.206, 0.240, 1.573, and 0.168, respectively; p < 0.05).