JMJD6 and cancer: The high‐levels of ‘oncometabolites’, e. g., 2‐hydroxysuccinate and fumarate, reached in some cancer cells suggest it is possible that JMJD6 inhibition is relevant to their roles in tumorigenesis, but the current biochemical evidence suggest that other 2OG oxygenases may be more potently inhibited by them than JMJD6 in cells, though lack of detailed knowledge on subcellular concentrations of enzymes and oncometabolites makes answering this question difficult.[18, 23, 26]