JMJD6 and cancer: In many cancer cells mutations to metabolic enzyme genes correlates with elevated levels of acidic metabolites, including succinate, fumarate, and 2‐hydroxyglutarate (2HG), which in turn are proposed to lead to inhibition of 2OG oxygenases (and other enzymes), in a manner promoting tumorigenesis / cancer development.[18] JMJD6 has not been investigated in this regard.