TET2 and lymphoma: Consistent with this notion, in AITL animal models, TET2 disruption or RHOAG17V expression alone failed to induce AITL development; however, AITL-like lymphoma developed once TET2 disruption and RHOAG17V expression were combined (Cortes et al., 2018; Ng et al., 2018; Nguyen et al., 2020).