While the DEMETER tool for cancer‐cell line dependencies illuminated no trend toward increased or decreased dependence on SP1 for MLL3‐mutant ER+ breast cancer cells lines compared to those that are MLL3‐WT (Figure 5D),38 we investigated the SP1‐binding patterns in ZR751shLucif and ZR751shMLL3. The gene discussed is KMT2C; the disease is cancer.