A Kaplan–Meier plot of TCGA breast cancer patients demonstrated that untreated ER+ breast cancer patients with MLL3‐mutant breast tumors have a significantly poorer overall survival than those with MLL3‐wildtype tumors (Figure 1H), suggesting that loss of MLL3 function contributes to poor outcomes in breast cancer patients. The gene discussed is KMT2C; the disease is breast carcinoma.