The prognostic significance of GLUT-1 expression in different cancer types such as osteosarcoma, gastric adenocarcinoma, esophagus adenocarcinoma, pancreatic carcinoma, lung carcinoma, oral squamous cell carcinoma, endometrial adenocarcinoma has been reported in numerous studies (23–30). The gene discussed is SLC2A1; the disease is esophageal adenocarcinoma.