These findings are in line with previous studies that showed that echinomycin suppressed the growth of multiple AML cell lines and T-lymphoblastic leukemia cell lines (Yonekura et al., 2013) and effectively treated a mouse Mll-Flt3 AML model (Wang et al., 2011b, 2014). This evidence concerns the gene KMT2A and acute myeloid leukemia.