AIH is subdivided into two types according to the serological profile: type 1 (AIH-1) is characterized by anti-nuclear antibody (ANA) and/or anti-smooth muscle antibody (SMA), whereas type 2 (AIH-2) is characterized by anti-liver-kidney microsomal antibody type 1 (anti-LKM1) and/or by anti-liver cytosol type 1 antibody (anti-LC1) [2]. The gene discussed is DNAL1; the disease is autoimmune hepatitis.