The disease was better characterized a few years later by the Swedish physician Waldenström, who presented at the meeting of the German Society for Digestive and Metabolic Disorders in 1950 his observations on six patients, five females, affected by a peculiar form of hepatitis (‘hepatitis sui generis’) with marked elevation of serum gamma globulins and amenorrhea, who had a striking improvement of symptoms and a dramatic fall of the erythrocyte sedimentation rate after administration of adrenocorticotropic hormone [5]. The gene discussed is POMC; the disease is hepatitis A virus infection.