Thus, a series of Lys-urea-Glu-based PSMA-targeted imaging agents with favorable biological properties emerged to visualize PCa lesions, such as 18F-DCFPyL, 18F-PSMA-1007, 68Ga-PSMA-1120, and 68Ga-PSMA-61721–24 (Fig. 1). Here, FOLH1 is linked to posterior cortical atrophy.