The present study evaluated the CNs for immunity-related non-MHC genes such as TNFAIP3, TNIP1, IL12B, TBX21 (T-bet), TLR7, CCL3L1, and CCL3L3, and MHC genes such as C4A and C4B using mrcPCR assays in 327 SLE patients and 338 controls. This evidence concerns the gene TLR7 and systemic lupus erythematosus.