Other genes significantly upregulated (Padjusted < 0.001) in non-epithelioid tumours included GPR176 which acts as a circadian pacesetter36, and known adverse factors for other cancers such as IGF2BP1, CCBE1, HS3ST3A1, TRAM2 and SERTAD2. This evidence concerns the gene HS3ST3A1 and neoplasm.