Cancer/testis antigens are a group of proteins, such as cancer/testis antigen 1 (CTAG1B, often referred to New York esophageal squamous cell carcinoma 1 or NY-ESO-1), melanoma-associated antigen 1 (MAGE-A1), MAGE-A3, etc., that are normally expressed in immune privileged germline cells, but upregulated in some cancer cells. Here, CTAG1B is linked to cancer.